cause of death in the United States after heart disease, cancer, and stroke.. In any case, 225000 deaths per year constitutes the third leading cause of death in the United States, after deaths from heart disease and cancer.. Motor vehicle injuries are the leading cause of death among children in the U.S. (CDC 2006). But many of these deaths can be prevented.. Third only to cancer and heart disease, doctor-induced disease is killing 250000 Americans Add Link Site every year. So says the Journal of the American Medical . Leading causes of death in the United States. Tierney

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